Single-molecule, single-photon methods are currently being used to examine dynamics and conformations of calmodulin and calmodulin target recognition and activation.
Current Single Molecule Studies
- Polarization Modulation Studies
- Burst Fluorescence Measurements
- Fluorescence Correlation Spectroscopy (FCS)
Time-correlated single-photon counting is one of many fluorescence techniques used in our lab to study problems such as the study of intramolecular attractions in model peptide systems.